منابع مشابه
C4qo00228h 1166..1171 ++
The human kinome comprises over 500 protein kinases. When mutated or over-expressed, many play critical roles in abnormal cellular functions associated with cancer, cardiovascular disease and neurological disorders. Here we report a step-economical approach to designed kinase inhibitors inspired by the potent, but non-selective, natural product staurosporine, and synthetically enabled by a nove...
متن کاملDmm021204 1155..1166
Novel genetically engineered mouse models using the Cre-loxP or the Flp-FRT systems have generated useful reagents to manipulate the mouse genome in a temporally-regulated and tissue-specific manner. By incorporating a constitutive Cre driver line into a mouse model in which FRT-regulated genes in other cell types are regulated by Flp-FRT recombinase, gene expression can be manipulated simultan...
متن کاملLimnol. Oceanogr., 44(4), 1999, 1166–1175
Seventeen sites in Florida Bay were sampled on a monthly basis for 51 months to describe the spatial and temporal patterns of phytoplankton blooms. The study focused on the picoplanktonic cyanobacterium Synechococcus. The greatest frequency and intensity of blooms was observed in the north-central region of Florida Bay, where cellular biovolumes of this species regularly exceeded 10 3 106 mm3 m...
متن کامل203 Ngoan
From 1956-70 among 6,668 female cancers, 3,023 cases (45% of female cancers) were cervical cancer reported by medical institutions in Ho Chi Minh City (HCM), south Viet Nam, (Hoanh et al., 1976). Thereafter, from 1976-81, a very high frequency of cervical cancer was also reported: 53% of the female cancer patients (3,602 of 6,757 cases) treated in the Central Oncology of Ho Chi Minh City, (Truo...
متن کاملBiol. Pharm. Bull. 30(6) 1164—1166 (2007)
fects, such as methyl brevifolincarboxylate, from the leaves of Phyllanthus niruri, ebricoic acid from the extract of Phellinus givus, and forsythiaside from the fruit of Forsythia suspensa. In our attempts to search for compounds with vasorelaxant effects from various plants, in the present study we isolated three constituents from the heartwood of Acer nikoense (Aceraceae): A. nikoense is a J...
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ژورنال
عنوان ژورنال: CALÍOPE: Presença Clássica
سال: 2017
ISSN: 2447-875X
DOI: 10.17074/cpc.v1i33.10141